Abnormalities of gait and mobility

R18_ABNORMALITI_GAIT_MOBIL

gait apraxia: Impaired ambulation not attributed to sensory impairment or motor weakness. frontal lobe disorders; basal ganglia diseases (e.g., parkinsonian disorders); dementia, multi-infarct; alzheimer disease; and other conditions may be associated with gait apraxia.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 R26
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 R26
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

2313

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2313

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Check minimum number of events None

2313

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Include endpoints None

2313

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R18_ABNORMALITI_GAIT_MOBIL

Extra metadata

Level in the ICD hierarchy 3
Special GAITCHANGE
First used in FinnGen datafreeze DF4
Parent code in ICD-10 R25-R29
Name in latin Abnormitates incessus et mobilitatis

Summary Statistics

Key figures

All Female Male
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Number of individuals
2232 1056 1176
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Unadjusted prevalence (%)
0.72 0.61 0.87
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Mean age at first event (years)
62.78 59.69 65.56

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Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 4.28 [2.82, 6.52] 1.1e-11 311
15 years 0.01 1.60 [1.04, 2.47] 3.2e-2 107
5 years 0.00 4.15 [2.77, 6.20] 4.5e-12 149
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: R18_ABNORMALITI_GAIT_MOBIL – Abnormalities of gait and mobility
GWS hits: 0

Survival analyses between endpoints

Plot

before Abnormalities of gait and mobility
after Abnormalities of gait and mobility

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Drugs most likely to be purchased after Abnormalities of gait and mobility