Congenital malformations of the circulatory system

DOID MESH PheWeb

Q17_CONGEN_MALFO_CIRCULATO_SYSTEM

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 Q20-Q28

Cause of death: ICD-10 Q20-Q28

3316

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

3316

Check minimum number of events None

3316

Include endpoints

Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO

Q17_CONGEN_MALFO_CARDIAC_SEPTA

Q17_CONGEN_MALFO_PULMONARY_TRICU_VALVES

Q17_CONGEN_MALFO_AORTIC_MITRAL_VALVES

Q17_OTHER_CONGEN_MALFO_HEART

Q17_CONGEN_MALFO_GREAT_ARTERIES

Q17_CONGEN_MALFO_GREAT_VEINS

Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM

Q17_OTHER_CONGEN_MALFO_CIRCULATO_SYSTEM

3385

Q17_CONGEN_MALFO_CIRCULATO_SYSTEM

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF4

Parent code in ICD-10 Q

Name in latin Malformationes congenitae systematis circulatorii

Similar endpoints

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List of similar endpoints to Congenital malformations of the circulatory system based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	3244	1725	1519
Unadjusted prevalence (%)	1.05	0.99	1.13
Mean age at first event (years)	39.03	37.01	41.31

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	4.21 [2.57, 6.88]	1.0e-8	151
15 years	0.02	2.49 [1.52, 4.07]	2.9e-4	74
5 years	0.00	4.12 [2.70, 6.31]	6.5e-11	40
1 year	0.00	13.11 [8.07, 21.29]	2.6e-25	25

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: Q17_CONGEN_MALFO_CIRCULATO_SYSTEM – Congenital malformations of the circulatory system
GWS hits: 2

Survival analyses between endpoints

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Plot

before Congenital malformations of the circulatory system
after Congenital malformations of the circulatory system

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Table

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Drugs most likely to be purchased after Congenital malformations of the circulatory system

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