Psoriasis (vulgaris), strict definition

PSORI_STRICT

psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None

321302

diagram downward connector
diagram bullet

Check conditions

L12_PSORI_VULG

4496

diagram downward connector
diagram bullet

Filter registries

KELA reimbursements: KELA codes 319|377|134

556

diagram downward connector

Check pre-conditions, main-only, mode, ICD version None

556

diagram downward connector

Check minimum number of events None

556

diagram downward connector

Include endpoints None

556

diagram downward connector
PSORI_STRICT

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 535 199 336
Unadjusted prevalence (%) 0.17 0.11 0.25
Mean age at first event (years) 51.13 51.40 50.96

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.69 [0.70, 4.10] 2.4e-1 23
15 years 0.01 1.01 [0.38, 2.70] 9.9e-1 12
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: PSORI_STRICT – Psoriasis (vulgaris), strict definition
GWS hits: 3

Survival analyses between endpoints

Plot

before Psoriasis (vulgaris), strict definition
after Psoriasis (vulgaris), strict definition

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Psoriasis (vulgaris), strict definition