Respiratory distress of newborn

P16_RESPI_DISTR_NEWBO

newborn respiratory distress syndrome: Infant acute respiratory distress syndrome is a lung disorder that affects premature infants caused by developmental insufficiency of surfactant production and structural immaturity of the lungs. The symptoms usually appear shortly after birth and may include tachypnea, tachycardia, chest wall retractions (recession), expiratory grunting, nasal flaring and cyanosis during breathing efforts.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 P22

Cause of death: ICD-10 P22

281

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

281

Check minimum number of events None

281

Include endpoints None

281

P16_RESPI_DISTR_NEWBO

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Parent code in ICD-10 P2

Name in latin Dyspnoea neonatalis

Similar endpoints

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List of similar endpoints to Respiratory distress of newborn based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	261	117	144
Unadjusted prevalence (%)	0.08	0.07	0.11
Mean age at first event (years)	0.21	0.46	0.00

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: P16_RESPI_DISTR_NEWBO – Respiratory distress of newborn
GWS hits: 0

Survival analyses between endpoints

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Plot

before Respiratory distress of newborn
after Respiratory distress of newborn

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Drugs most likely to be purchased after Respiratory distress of newborn

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