Intrahepatic Cholestasis of Pregnancy (ICP) 

O15_ICP

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule

Sex only females

180574

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Check conditions None

180574

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Filter registries

Hospital Discharge: ICD-10 O26.6
Hospital discharge: ICD-9 6467
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 O26.6
Cause of death: ICD-9 6467
Cause of death: ICD-8 $!$

1512

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1512

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Check minimum number of events None

1512

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Include endpoints None

1512

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O15_ICP

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3
Parent code in ICD-10 O26
Name in latin Morbositates hepatis in graviditate, intra labores et/sive in puerperio

Summary Statistics

Key figures

All Female Male
?
Number of individuals
1460 1460 -
?
Unadjusted prevalence (%)
0.47 0.84 -
?
Mean age at first event (years)
30.64 30.64 -

?
Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.21 [1.04, 4.67] 3.8e-2 11
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: O15_ICP – Intrahepatic Cholestasis of Pregnancy (ICP) 
GWS hits: 12

Survival analyses between endpoints

Plot

before Intrahepatic Cholestasis of Pregnancy (ICP) 
after Intrahepatic Cholestasis of Pregnancy (ICP) 

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Drugs most likely to be purchased after Intrahepatic Cholestasis of Pregnancy (ICP)