Spontaneous abortion

O15_ABORT_SPONTAN

habitual abortion: Three or more consecutive spontaneous abortions.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector
diagram bullet

Apply sex-specific rule

Sex only females

180574

diagram downward connector

Check conditions None

180574

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 O03
Hospital discharge: ICD-9 634
Hospital discharge: ICD-8 643
Cause of death: ICD-10 O03
Cause of death: ICD-9 634
Cause of death: ICD-8 643

19586

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

13859

diagram downward connector

Check minimum number of events None

13859

diagram downward connector

Include endpoints None

13859

diagram downward connector
O15_ABORT_SPONTAN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5
Parent code in ICD-10 O00-O08
Name in latin Abortus spontaneus

Summary Statistics

Key figures

All Female Male
Number of individuals 13354 13354 -
Unadjusted prevalence (%) 4.33 7.70 -
Mean age at first event (years) 30.38 30.38 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.48 [0.37, 0.62] 2.3e-8 213
15 years 0.00 0.39 [0.29, 0.53] 6.3e-10 87
5 years 0.00 0.27 [0.15, 0.51] 5.1e-5 11
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: O15_ABORT_SPONTAN – Spontaneous abortion
GWS hits: 2

Survival analyses between endpoints

Plot

before Spontaneous abortion
after Spontaneous abortion

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Spontaneous abortion