Tubulo-interstitial nephritis, not spesified as acute or chronic

N14_TUBULOINTNEPHRNAS

pyelonephritis: Inflammation of the KIDNEY involving the renal parenchyma (the NEPHRONS); KIDNEY PELVIS; and KIDNEY CALICES. It is characterized by ABDOMINAL PAIN; FEVER; NAUSEA; VOMITING; and occasionally DIARRHEA.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 N12
Hospital discharge: ICD-9 5909
Hospital discharge: ICD-8 5909
Cause of death: ICD-10 N12
Cause of death: ICD-9 5909
Cause of death: ICD-8 5909

1723

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1723

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Check minimum number of events None

1723

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Include endpoints None

1723

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N14_TUBULOINTNEPHRNAS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N10-N16
Name in latin Nephritis tubulo-interstitialis sine specificatione utrum acuta an chronica

Summary Statistics

Key figures

All Female Male
Number of individuals 1662 1036 626
Unadjusted prevalence (%) 0.54 0.60 0.46
Mean age at first event (years) 52.90 46.32 63.79

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 5.26 [3.36, 8.24] 4.4e-13 381
15 years 0.01 1.29 [0.81, 2.06] 2.9e-1 87
5 years 0.00 4.20 [2.72, 6.49] 9.5e-11 128
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: N14_TUBULOINTNEPHRNAS – Tubulo-interstitial nephritis, not spesified as acute or chronic
GWS hits: 0

Survival analyses between endpoints

Plot

before Tubulo-interstitial nephritis, not spesified as acute or chronic
after Tubulo-interstitial nephritis, not spesified as acute or chronic

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Drugs most likely to be purchased after Tubulo-interstitial nephritis, not spesified as acute or chronic