Other specified disorders of kidney and ureter

N14_OTHETNASKIDUR

renal artery obstruction: Narrowing or occlusion of the renal artery or arteries. It is due usually to atherosclerosis; fibromuscular dysplasia; thrombosis; embolism, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (hypertension, renovascular).

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 N28.0, N28.8, N28.9

Hospital discharge: ICD-9 593[0-1]|5938

Hospital discharge: ICD-8 59322

Hospital discharge: excluded ICD-8 5938B

Cause of death: ICD-10 N28.0, N28.8, N28.9

Cause of death: ICD-9 593[0-1]|5938

Cause of death: ICD-8 59322

Cause of death: excluded ICD-8 5938B

752

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

688

Check minimum number of events None

688

Include endpoints None

688

N14_OTHETNASKIDUR

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other specified disorders of kidney and ureter based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	669	362	307
Unadjusted prevalence (%)	0.22	0.21	0.23
Mean age at first event (years)	49.77	46.21	53.96

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.07	5.44 [3.32, 8.90]	1.6e-11	85
15 years	0.02	2.91 [1.81, 4.67]	9.8e-6	37
5 years	0.01	6.06 [3.74, 9.81]	2.3e-13	29
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_OTHETNASKIDUR – Other specified disorders of kidney and ureter
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other specified disorders of kidney and ureter
after Other specified disorders of kidney and ureter

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Table

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Drugs most likely to be purchased after Other specified disorders of kidney and ureter

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