Male infertility

N14_MALEINFERT

male infertility: The inability of the male to effect fertilization of an ovum after a specified period of unprotected intercourse. Male sterility is permanent infertility.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule

Sex only males

140728

Check conditions None

140728

Filter registries

Hospital Discharge: ICD-10 N46

Hospital discharge: ICD-9 606

Hospital discharge: ICD-8 606

Cause of death: ICD-10 N46

Cause of death: ICD-9 606

Cause of death: ICD-8 606

1060

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1060

Check minimum number of events None

1060

Include endpoints None

1060

N14_MALEINFERT

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 N40-N51

Name in latin Infertilitas masculina

Similar endpoints

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List of similar endpoints to Male infertility based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	994	-	994
Unadjusted prevalence (%)	0.32	-	0.74
Mean age at first event (years)	34.55	-	34.55

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.13	9.64 [4.94, 18.83]	3.2e-11	13
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_MALEINFERT – Male infertility
GWS hits: 1

Survival analyses between endpoints

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Plot

before Male infertility
after Male infertility

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Male infertility

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