Male infertility


male infertility: The inability of the male to effect fertilization of an ovum after a specified period of unprotected intercourse. Male sterility is permanent infertility.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule

Sex only males


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 N46
Hospital discharge: ICD-9 606
Hospital discharge: ICD-8 606
Cause of death: ICD-10 N46
Cause of death: ICD-9 606
Cause of death: ICD-8 606


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N40-N51
Name in latin Infertilitas masculina

Summary Statistics

Key figures

All Female Male
Number of individuals 994 - 994
Unadjusted prevalence (%) 0.32 - 0.74
Mean age at first event (years) 34.55 - 34.55


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.13 9.64 [4.94, 18.83] 3.2e-11 13
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: N14_MALEINFERT – Male infertility
GWS hits: 1

Survival analyses between endpoints


before Male infertility
after Male infertility

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Drugs most likely to be purchased after Male infertility