Hydronephrosis

N14_HYDRONEPHR

hydronephrosis: Collection of urine in the renal pelvis that results in dilatation of the renal pelvis and calyces. It is caused by obstruction of urine flow, nephrolithiasis, or vesicoureteral reflux. Signs and symptoms include flank pain, nausea, vomiting, fever, and dysuria.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 N13.0, N13.1, N13.2, N13.3

Hospital discharge: ICD-9 591

Hospital discharge: ICD-8 591

Cause of death: ICD-10 N13.0, N13.1, N13.2, N13.3

Cause of death: ICD-9 591

Cause of death: ICD-8 591

2415

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2415

Check minimum number of events None

2415

Include endpoints None

2415

N14_HYDRONEPHR

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Hydronephrosis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2318	1110	1208
Unadjusted prevalence (%)	0.75	0.64	0.89
Mean age at first event (years)	56.76	51.52	61.57

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.81 [2.91, 7.95]	8.8e-10	486
15 years	0.01	1.28 [0.85, 1.94]	2.4e-1	96
5 years	0.01	5.21 [3.73, 7.28]	4.2e-22	154
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_HYDRONEPHR – Hydronephrosis
GWS hits: 0

Survival analyses between endpoints

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Plot

before Hydronephrosis
after Hydronephrosis

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Hydronephrosis

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