Inflammatory diseases of female pelvic organs

N14_FEMALEGENINF

Pelvic Inflammatory Disease: Pelvic inflammatory disease (PID) is an acute or chronic inflammation in the pelvic cavity. It is most commonly caused by sexually transmitted diseases, including chlamydia and gonorrhea that have ascended into the uterus, fallopian tubes, or ovaries as a result of intercourse or childbirth, or of surgical procedures, including insertion of IUDs or abortion. PID may be either symptomatic or asymptomatic. It may cause infertility and it may raise the risk of ectopic pregnancy. PID is a disease associated with HIV infection.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule

Sex only females

180574

Check conditions None

180574

Filter registries

Hospital Discharge: ICD-10 N70-N77

Cause of death: ICD-10 N70-N77

10891

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

10891

Check minimum number of events None

10891

Include endpoints

N14_SALPHOOPH

N14_INFLUTH

N14_INFCERVIX

N14_OTHFEMPELINF

N14_FEMPELINFINOTH

N14_BARTHOCYS

N14_BARTHOABSCESS

N14_BARTHOOTHNAS

N14_VAGINITIS

N14_ULCERVAGVUL

N14_OTHINFVAGVULV

N14_VULVOVAGINFINOTH

17684

N14_FEMALEGENINF

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Inflammatory diseases of female pelvic organs based on the number of shared cases.

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	17022	17022	-
Unadjusted prevalence (%)	5.52	9.81	-
Mean age at first event (years)	35.81	35.81	-

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.70 [0.57, 0.86]	6.0e-4	557
15 years	0.00	0.48 [0.39, 0.60]	3.7e-11	219
5 years	0.00	0.66 [0.49, 0.88]	5.4e-3	61
1 year	0.00	1.30 [0.82, 2.06]	2.6e-1	21

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_FEMALEGENINF – Inflammatory diseases of female pelvic organs
GWS hits: 1

Survival analyses between endpoints

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Plot

before Inflammatory diseases of female pelvic organs
after Inflammatory diseases of female pelvic organs

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Drugs most likely to be purchased after Inflammatory diseases of female pelvic organs

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