Dysplasia of cervi uteri

N14_DYSPLACERVUT

dysplasia of cervix: Abnormal development of immature squamous epithelial cells of the uterine cervix, a term used to describe premalignant cytological changes in the cervical epithelium. These atypical cells do not penetrate the epithelial basement membrane.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule

Sex only females

180574

Check conditions None

180574

Filter registries

Hospital Discharge: ICD-10 N87

Hospital discharge: ICD-9 6221

Hospital discharge: ICD-8 621

Hospital discharge: excluded ICD-8 62191

Cause of death: ICD-10 N87

Cause of death: ICD-9 6221

Cause of death: ICD-8 621

Cause of death: excluded ICD-8 62191

8289

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

6643

Check minimum number of events None

6643

Include endpoints None

6643

N14_DYSPLACERVUT

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 N80-N98

Name in latin Dysplasia cervicis uteri

Similar endpoints

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List of similar endpoints to Dysplasia of cervi uteri based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

6397

Unadjusted prevalence (%)

2.07

3.69

Mean age at first event (years)

36.46

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Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.66 [0.34, 1.26]	2.1e-1	145
15 years	0.00	0.52 [0.28, 0.95]	3.5e-2	65
5 years	0.00	0.80 [0.41, 1.54]	5.0e-1	20
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_DYSPLACERVUT – Dysplasia of cervi uteri
GWS hits: 1

Survival analyses between endpoints

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Plot

before Dysplasia of cervi uteri
after Dysplasia of cervi uteri

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Table

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Drugs most likely to be purchased after Dysplasia of cervi uteri

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