Disorders resulting from impaired renal tubular function

DOID EFO MESH SNOMED PheWeb

N14_DISIMPAIRRENTUB

urinary system disease: A disease involving the renal system. [database_cross_reference: MONDO:DesignPattern]

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 N25

Hospital discharge: ICD-9 588

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 N25

Cause of death: ICD-9 588

Cause of death: ICD-8 $!$

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

681

N14_DISIMPAIRRENTUB

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 N25-N29

Name in latin Morbositates ex dysfunctione tubulari renali

Similar endpoints

↥

List of similar endpoints to Disorders resulting from impaired renal tubular function based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	653	303	350
Unadjusted prevalence (%)	0.21	0.17	0.26
Mean age at first event (years)	55.36	53.73	56.77

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.10	7.87 [4.07, 15.22]	9.0e-10	91
15 years	0.01	2.18 [1.02, 4.64]	4.5e-2	24
5 years	0.01	7.85 [4.00, 15.42]	2.1e-9	44
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: N14_DISIMPAIRRENTUB – Disorders resulting from impaired renal tubular function
GWS hits:

Survival analyses between endpoints

↥

Plot

before Disorders resulting from impaired renal tubular function
after Disorders resulting from impaired renal tubular function

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Disorders resulting from impaired renal tubular function

↥