Disorders of breast

DOID EFO MESH SNOMED PheWeb

N14_BREAST

breast disease: A disease involving the breast.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule

Sex only females

180574

Check conditions None

180574

Filter registries

Hospital Discharge: ICD-10 N60-N64

Cause of death: ICD-10 N60-N64

10917

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

10917

Check minimum number of events None

10917

Include endpoints

N14_BENIGNMAMDYSP

N14_INFLAMMBREAST

N14_HYPERTROPHYBREAST

N14_LUMPNASBREAST

N14_BREASTDISOTH

13408

N14_BREAST

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Disorders of breast based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	12936	12936	-
Unadjusted prevalence (%)	4.19	7.45	-
Mean age at first event (years)	46.17	46.17	-

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.77 [0.62, 0.95]	1.3e-2	523
15 years	0.00	0.57 [0.46, 0.70]	1.9e-7	239
5 years	0.00	0.93 [0.72, 1.20]	5.6e-1	90
1 year	0.00	0.81 [0.46, 1.40]	4.4e-1	14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_BREAST – Disorders of breast
GWS hits: 6

Survival analyses between endpoints

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Plot

before Disorders of breast
after Disorders of breast

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Table

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Drugs most likely to be purchased after Disorders of breast

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