Disorders of breast

N14_BREAST

breast disease: A disease involving the breast.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule

Sex only females

180574

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Check conditions None

180574

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Filter registries

Hospital Discharge: ICD-10 N60-N64
Cause of death: ICD-10 N60-N64

10917

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

10917

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Check minimum number of events None

10917

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N14_BREAST

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 12936 12936 -
Unadjusted prevalence (%) 4.19 7.45 -
Mean age at first event (years) 46.17 46.17 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.77 [0.62, 0.95] 1.3e-2 523
15 years 0.00 0.57 [0.46, 0.70] 1.9e-7 239
5 years 0.00 0.93 [0.72, 1.20] 5.6e-1 90
1 year 0.00 0.81 [0.46, 1.40] 4.4e-1 14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: N14_BREAST – Disorders of breast
GWS hits: 6

Survival analyses between endpoints

Plot

before Disorders of breast
after Disorders of breast

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Drugs most likely to be purchased after Disorders of breast