Non-selective monoamine reuptake inhibitors

PheWeb

MRI_NONSEL

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Medicine purchases: ATC N06AA

25684

Check pre-conditions, main-only, mode, ICD version None

12463

Check minimum number of events

Min. number of events 3

12463

Include endpoints None

12463

MRI_NONSEL

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Non-selective monoamine reuptake inhibitors based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	12121	8009	4112
Unadjusted prevalence (%)	3.93	4.62	3.05
Mean age at first event (years)	48.47	47.57	50.21

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.66 [1.32, 2.08]	1.3e-5	1397
15 years	0.01	1.35 [1.12, 1.63]	1.8e-3	726
5 years	0.00	1.74 [1.46, 2.08]	1.1e-9	245
1 year	0.00	1.95 [1.44, 2.64]	1.4e-5	52

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: MRI_NONSEL – Non-selective monoamine reuptake inhibitors
GWS hits:

Survival analyses between endpoints

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Plot

before Non-selective monoamine reuptake inhibitors
after Non-selective monoamine reuptake inhibitors

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Table

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Drugs most likely to be purchased after Non-selective monoamine reuptake inhibitors

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