Other disorders of the musculoskeletal system and connective tissue

M13_MUSCULOSKELEOTH

musculoskeletal system disease: A disease involving the musculoskeletal system. [database_cross_reference: MONDO:DesignPattern]

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M95-M99

Cause of death: ICD-10 M95-M99

2110

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

2110

Check minimum number of events None

2110

Include endpoints

M13_DEFORMACQ

M13_POSTOPMUSCULOSKE

M13_BIOMECHLESIO

3123

M13_MUSCULOSKELEOTH

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other disorders of the musculoskeletal system and connective tissue based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	3007	1677	1330
Unadjusted prevalence (%)	0.97	0.97	0.99
Mean age at first event (years)	49.41	48.49	50.57

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.81 [1.02, 3.23]	4.4e-2	261
15 years	0.01	1.14 [0.72, 1.81]	5.8e-1	107
5 years	0.00	2.45 [1.66, 3.63]	7.3e-6	64
1 year	0.00	3.62 [2.10, 6.23]	3.4e-6	18

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_MUSCULOSKELEOTH – Other disorders of the musculoskeletal system and connective tissue
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other disorders of the musculoskeletal system and connective tissue
after Other disorders of the musculoskeletal system and connective tissue

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Table

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Drugs most likely to be purchased after Other disorders of the musculoskeletal system and connective tissue

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