Other and unspecified psoriasis

L12_PSORI_NAS

psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L40.8, L40.9

Hospital discharge: ICD-9 6968X

Hospital discharge: ICD-8 69619

Cause of death: ICD-10 L40.8, L40.9

Cause of death: ICD-9 6968X

Cause of death: ICD-8 69619

1321

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1321

Check minimum number of events None

1321

Include endpoints None

1321

L12_PSORI_NAS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unspecified psoriasis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1287	623	664
Unadjusted prevalence (%)	0.42	0.36	0.49
Mean age at first event (years)	47.04	44.80	49.14

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.36 [1.54, 3.61]	7.5e-5	165
15 years	0.01	1.47 [0.97, 2.23]	7.1e-2	78
5 years	0.00	2.59 [1.67, 4.04]	2.4e-5	44
1 year	0.00	4.04 [2.15, 7.59]	1.5e-5	13

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_PSORI_NAS – Other and unspecified psoriasis
GWS hits: 3

Survival analyses between endpoints

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Plot

before Other and unspecified psoriasis
after Other and unspecified psoriasis

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Other and unspecified psoriasis

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