Lichen simplex chronicus and prurigo

L12_LICHSIMPANDPRURIGO

neurodermatitis: an itchy skin disease similar to atopic dermatitis. It tends to result in focal patches—one or many—that are due to frequent rubbing or scratching of the same area over time.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L28

Cause of death: ICD-10 L28

1236

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

1236

Check minimum number of events None

1236

Include endpoints

L12_LICHENSIMPLEX

L12_PRURIGONOD

L12_PRURIGONAS

1304

L12_LICHSIMPANDPRURIGO

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L20-L30

Name in latin Neurodermatitis

Similar endpoints

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List of similar endpoints to Lichen simplex chronicus and prurigo based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1266	735	531
Unadjusted prevalence (%)	0.41	0.42	0.39
Mean age at first event (years)	54.04	53.11	55.33

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.61 [0.92, 2.82]	9.8e-2	110
15 years	0.01	1.23 [0.74, 2.05]	4.3e-1	56
5 years	0.00	2.53 [1.60, 3.98]	6.4e-5	34
1 year	0.00	3.81 [1.94, 7.47]	1.0e-4	10

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_LICHSIMPANDPRURIGO – Lichen simplex chronicus and prurigo
GWS hits: 2

Survival analyses between endpoints

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Plot

before Lichen simplex chronicus and prurigo
after Lichen simplex chronicus and prurigo

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Table

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Drugs most likely to be purchased after Lichen simplex chronicus and prurigo

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