Disorders of skin appendages

DOID MESH PheWeb

L12_DISORDSKINAPPENDIX

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L60-L75

Cause of death: ICD-10 L60-L75

11035

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

11035

Check minimum number of events None

11035

Include endpoints

L12_NAILDIS

L12_ALOPECAREATA

L12_ALOPECANDRO

L12_HAIRLOSSNONSCAR

L12_HAIRLOSSSCAR

L12_HAIRLOSSNAS

L12_HAIRCOLOUR

L12_HYPERTRICHOSIS

L12_ACNE

L12_ROSACEA

L12_FOLLICULARCYST

L12_FOLICULAROTH

L12_ECCRINESWEAT

L12_APOCRINESWEAT

12065

L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Disorders of skin appendages based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	11610	6899	4711
Unadjusted prevalence (%)	3.76	3.98	3.49
Mean age at first event (years)	45.06	44.40	46.03

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.37 [1.85, 3.05]	1.2e-11	614
15 years	0.01	1.57 [1.21, 2.04]	7.5e-4	313
5 years	0.00	2.46 [1.95, 3.11]	5.2e-14	159
1 year	0.00	3.68 [2.62, 5.17]	6.6e-14	46

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_DISORDSKINAPPENDIX – Disorders of skin appendages
GWS hits: 1

Survival analyses between endpoints

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Plot

before Disorders of skin appendages
after Disorders of skin appendages

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Table

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Drugs most likely to be purchased after Disorders of skin appendages

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