Acute generalized exanthematous pustulosis

PheWeb

L12_AGEP

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L27.0#, L53.8

Hospital discharge: ICD-9 6959X

Hospital discharge: ICD-8 69599

Cause of death: ICD-10 L27.0#, L53.8

Cause of death: ICD-9 6959X

Cause of death: ICD-8 69599

910

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

910

Check minimum number of events None

910

Include endpoints None

910

L12_AGEP

Extra metadata

First used in FinnGen datafreeze DF7

Similar endpoints

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List of similar endpoints to Acute generalized exanthematous pustulosis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Generalized skin eruption due to drugs and medicaments

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	883	601	282
Unadjusted prevalence (%)	0.29	0.35	0.21
Mean age at first event (years)	51.54	50.00	54.81

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.08	6.89 [4.60, 10.30]	6.2e-21	98
15 years	0.02	2.56 [1.70, 3.84]	6.5e-6	34
5 years	0.01	5.02 [3.09, 8.16]	7.3e-11	34
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_AGEP – Acute generalized exanthematous pustulosis
GWS hits:

Survival analyses between endpoints

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Plot

before Acute generalized exanthematous pustulosis
after Acute generalized exanthematous pustulosis

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Table

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Drugs most likely to be purchased after Acute generalized exanthematous pustulosis

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