Coalworker pneumoconiosis

J10_COALPNEUMOC

anthracosis: A diffuse parenchymal lung disease caused by accumulation of inhaled CARBON or coal dust. The disease can progress from asymptomatic anthracosis to massive lung fibrosis. This lung lesion usually occurs in coal MINERS, but can be seen in urban dwellers and tobacco smokers.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 J60
Hospital discharge: ICD-9 500
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 J60
Cause of death: ICD-9 500
Cause of death: ICD-8 $!$

17212

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

17

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Check minimum number of events None

17

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Include endpoints None

17

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J10_COALPNEUMOC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 J60-J70
Name in latin Anthracosis pulmonum

Summary Statistics

Key figures

All Female Male
Number of individuals 16 6 10
Unadjusted prevalence (%) 0.01 0.00 0.01
Mean age at first event (years) 53.47 52.58 54.00

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: J10_COALPNEUMOC – Coalworker pneumoconiosis
GWS hits:

Survival analyses between endpoints

Plot

before Coalworker pneumoconiosis
after Coalworker pneumoconiosis

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Drugs most likely to be purchased after Coalworker pneumoconiosis