Increased muscle tone

MESH PheWeb

INCREASEDMUSCLETONE

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 R29.0, R29.3

Hospital discharge: ICD-9 7817

Hospital discharge: ICD-8 78850

Cause of death: ICD-10 R29.0, R29.3

Cause of death: ICD-9 7817

Cause of death: ICD-8 78850

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints

M13_MUSCONTRAC

141

INCREASEDMUSCLETONE

Extra metadata

First used in FinnGen datafreeze DF3

Similar endpoints

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List of similar endpoints to Increased muscle tone based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Contracture of muscle

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	137	83	54
Unadjusted prevalence (%)	0.04	0.05	0.04
Mean age at first event (years)	46.74	43.24	52.13

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: INCREASEDMUSCLETONE – Increased muscle tone
GWS hits: 0

Survival analyses between endpoints

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Plot

before Increased muscle tone
after Increased muscle tone

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Increased muscle tone

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