Chronic viral hepatitis

HEPATITIS_CHRONIC_VIRAL

hepatitis A virus infection: Acute inflammation of the liver caused by the hepatitis A virus. It is highly contagious and usually contracted through close contact with an infected individual or their feces, contaminated food or water.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 B18
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 B18
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

1382

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1382

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Check minimum number of events None

1382

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Include endpoints None

1382

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HEPATITIS_CHRONIC_VIRAL

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 B15-B19
Name in latin Hepatitis viralis chronica

Summary Statistics

Key figures

All Female Male
Number of individuals 1250 502 748
Unadjusted prevalence (%) 0.41 0.29 0.55
Mean age at first event (years) 38.30 37.28 38.98

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.19 16.28 [9.32, 28.43] 1.1e-22 73
15 years 0.04 6.43 [3.28, 12.60] 5.7e-8 24
5 years 0.02 21.13 [12.19, 36.63] 1.6e-27 28
1 year 0.01 50.50 [26.34, 96.85] 3.6e-32 17

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: HEPATITIS_CHRONIC_VIRAL – Chronic viral hepatitis
GWS hits:

Survival analyses between endpoints

Plot

before Chronic viral hepatitis
after Chronic viral hepatitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Chronic viral hepatitis