Sudden idiopathic hearing loss

H8_HL_IDIOP

sensorineural hearing loss: Hearing loss in which the root cause lies in the inner ear or sensory organ (cochlea and associated structures) or the vestibulocochlear nerve (cranial nerve VIII).

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H91.2

Hospital discharge: ICD-9 3882

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 H91.2

Cause of death: ICD-9 3882

Cause of death: ICD-8 $!$

2272

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2272

Check minimum number of events None

2272

Include endpoints None

2272

H8_HL_IDIOP

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H91

Name in latin Hypacusis acuta idiopathica

Similar endpoints

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List of similar endpoints to Sudden idiopathic hearing loss based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2204	1145	1059
Unadjusted prevalence (%)	0.71	0.66	0.78
Mean age at first event (years)	56.73	54.90	58.70

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.47 [0.99, 2.18]	5.5e-2	141
15 years	0.01	0.89 [0.59, 1.34]	5.9e-1	65
5 years	0.00	1.93 [1.30, 2.86]	1.1e-3	44
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H8_HL_IDIOP – Sudden idiopathic hearing loss
GWS hits: 1

Survival analyses between endpoints

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Plot

before Sudden idiopathic hearing loss
after Sudden idiopathic hearing loss

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Table

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Drugs most likely to be purchased after Sudden idiopathic hearing loss

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