Retinoschisis and retinal cysts


retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 H33.1
Hospital discharge: ICD-9 3611
Hospital discharge: ICD-8 37603
Cause of death: ICD-10 H33.1
Cause of death: ICD-9 3611
Cause of death: ICD-8 37603


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H33
Name in latin Retinoschisis et cystae retinales

Summary Statistics

Key figures

All Female Male
Number of individuals 457 211 246
Unadjusted prevalence (%) 0.15 0.12 0.18
Mean age at first event (years) 60.27 59.04 61.33


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.42 [0.18, 0.98] 4.5e-2 27
15 years 0.00 0.41 [0.18, 0.93] 3.3e-2 17
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: H7_RETINOCHISISCYST – Retinoschisis and retinal cysts
GWS hits: 0

Survival analyses between endpoints


before Retinoschisis and retinal cysts
after Retinoschisis and retinal cysts

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Drugs most likely to be purchased after Retinoschisis and retinal cysts