Retinoschisis and retinal cysts

H7_RETINOCHISISCYST

retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H33.1

Hospital discharge: ICD-9 3611

Hospital discharge: ICD-8 37603

Cause of death: ICD-10 H33.1

Cause of death: ICD-9 3611

Cause of death: ICD-8 37603

472

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

472

Check minimum number of events None

472

Include endpoints None

472

H7_RETINOCHISISCYST

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H33

Name in latin Retinoschisis et cystae retinales

Similar endpoints

↥

List of similar endpoints to Retinoschisis and retinal cysts based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	457	211	246
Unadjusted prevalence (%)	0.15	0.12	0.18
Mean age at first event (years)	60.27	59.04	61.33

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.42 [0.18, 0.98]	4.5e-2	27
15 years	0.00	0.41 [0.18, 0.93]	3.3e-2	17
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: H7_RETINOCHISISCYST – Retinoschisis and retinal cysts
GWS hits: 0

Survival analyses between endpoints

↥

Plot

before Retinoschisis and retinal cysts
after Retinoschisis and retinal cysts

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Retinoschisis and retinal cysts

↥