Retinal detachment with retinal break

H7_RETINALDETACHBREAK

retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H33.0

Hospital discharge: ICD-9 3610

Hospital discharge: ICD-8 37602

Cause of death: ICD-10 H33.0

Cause of death: ICD-9 3610

Cause of death: ICD-8 37602

2971

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2947

Check minimum number of events None

2947

Include endpoints None

2947

H7_RETINALDETACHBREAK

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H33

Name in latin Amotio/ablatio retinae cum ruptura

Similar endpoints

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List of similar endpoints to Retinal detachment with retinal break based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Cerclage (due to retinal detachment, surrounding the bulbus 360 degrees)

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2862	1237	1625
Unadjusted prevalence (%)	0.93	0.71	1.20
Mean age at first event (years)	58.38	56.86	59.54

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.30 [0.91, 1.87]	1.5e-1	284
15 years	0.01	0.86 [0.60, 1.24]	4.2e-1	158
5 years	0.00	1.41 [0.97, 2.04]	7.2e-2	77
1 year	0.00	1.52 [0.84, 2.74]	1.7e-1	15

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_RETINALDETACHBREAK – Retinal detachment with retinal break
GWS hits: 0

Survival analyses between endpoints

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Plot

before Retinal detachment with retinal break
after Retinal detachment with retinal break

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Table

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Drugs most likely to be purchased after Retinal detachment with retinal break

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