Pterygium

H7_PTERYGIUM

pterygium: A wedge-shaped fibrovascular lesion arising from the bulbar conjunctiva and extending to the cornea. It is caused by chronic exposure to solar ultraviolet radiation, heat, and dust. It may cause severe vision loss. Studies have linked pterygium to neoplastic proliferation and suggest that it may be a stem cell disorder.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H11.0

Hospital discharge: ICD-9 3724

Hospital discharge: ICD-8 372

Cause of death: ICD-10 H11.0

Cause of death: ICD-9 3724

Cause of death: ICD-8 372

753

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

602

Check minimum number of events None

602

Include endpoints None

602

H7_PTERYGIUM

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H11

Name in latin Pterygium

Similar endpoints

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List of similar endpoints to Pterygium based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	567	206	361
Unadjusted prevalence (%)	0.18	0.12	0.27
Mean age at first event (years)	58.93	56.30	60.43

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.81 [1.15, 2.85]	9.8e-3	58
15 years	0.01	1.26 [0.81, 1.98]	3.1e-1	32
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_PTERYGIUM – Pterygium
GWS hits: 0

Survival analyses between endpoints

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Plot

before Pterygium
after Pterygium

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Table

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Drugs most likely to be purchased after Pterygium

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