Peripheral retinal degeneration

H7_PERIPHRETINADEGEN

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 H35.4
Hospital discharge: ICD-9 3626
Hospital discharge: ICD-8 37711
Cause of death: ICD-10 H35.4
Cause of death: ICD-9 3626
Cause of death: ICD-8 37711

649

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

649

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Check minimum number of events None

649

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Include endpoints None

649

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H7_PERIPHRETINADEGEN

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H35
Name in latin Degeneratio peripherica retinae

Summary Statistics

Key figures

All Female Male
?
Number of individuals
623 386 237
?
Unadjusted prevalence (%)
0.20 0.22 0.18
?
Mean age at first event (years)
51.85 50.17 54.58

?
Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 1.02 [0.49, 2.11] 9.7e-1 37
15 years 0.00 0.59 [0.27, 1.31] 2.0e-1 17
5 years - - - -
1 year - - - -

Age distribution of first events

020304050607080020406080100120140ageindividuals

Year distribution of first events

19701980198519901995200020052010201520210102030405060708090100110120130yearindividuals

Cumulative Incidence

01020304050607080901000102030405060708090100agecumulative incidence (%)

Correlations

Index endpoint: H7_PERIPHRETINADEGEN – Peripheral retinal degeneration
GWS hits: 0

Correlated endpoint

Case-control overlap (%)

GWS hits

Coloc GWS hits (same dir)

Relative β with index

Coloc GWS hits (opp dir)

0.19
7
0
0
0
0.11
3
0
0
0

Survival analyses between endpoints

Plot

before Peripheral retinal degeneration
after Peripheral retinal degeneration

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Drugs most likely to be purchased after Peripheral retinal degeneration