Paralytic strabismus

H7_PARASTRAB

paralytic strabismus: An ocular deviation caused by a palsy to one or more of the extraocular muscles or nerves supplying them. [database_cross_reference: ORCID:0000-0003-0986-4123][database_cross_reference: ORCID:0000-0003-0986-4123]

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H49

Cause of death: ICD-10 H49

1371

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

1371

Check minimum number of events None

1371

Include endpoints

H7_PARASTRA3

H7_PARASTRA4

H7_PARASTRA6

H7_TOTALOPHTHALMOPLEGIA

H7_PROGEXTOPHTHALMOPLEGIA

H7_PARASTRANAS

1456

H7_PARASTRAB

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H49-H52

Name in latin Strabismus paralyticus

Similar endpoints

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List of similar endpoints to Paralytic strabismus based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

1405

694

711

Unadjusted prevalence (%)

0.46

0.40

0.53

Mean age at first event (years)

56.98

54.37

59.54

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Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.74 [1.06, 2.86]	2.8e-2	174
15 years	0.01	0.96 [0.61, 1.51]	8.6e-1	78
5 years	0.00	1.81 [1.16, 2.84]	9.2e-3	46
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_PARASTRAB – Paralytic strabismus
GWS hits: 1

Survival analyses between endpoints

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Plot

before Paralytic strabismus
after Paralytic strabismus

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Table

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Drugs most likely to be purchased after Paralytic strabismus

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