Other and unspecified glaucoma

DOID EFO MESH SNOMED PheWeb

H7_GLAUCNAS

glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H40.8, H40.9

Hospital discharge: ICD-9 3656X|3656C|365[8-9]

Hospital discharge: ICD-8 3752|3759

Hospital discharge: excluded ICD-8 37597

Cause of death: ICD-10 H40.8, H40.9

Cause of death: ICD-9 3656X|3656C|365[8-9]

Cause of death: ICD-8 3752|3759

Cause of death: excluded ICD-8 37597

1265

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1253

Check minimum number of events None

1253

Include endpoints None

1253

H7_GLAUCNAS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unspecified glaucoma based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1214	677	537
Unadjusted prevalence (%)	0.39	0.39	0.40
Mean age at first event (years)	64.84	65.70	63.75

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.11 [1.36, 3.28]	8.7e-4	237
15 years	0.01	0.87 [0.56, 1.35]	5.2e-1	89
5 years	0.00	2.32 [1.55, 3.46]	3.8e-5	90
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_GLAUCNAS – Other and unspecified glaucoma
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other and unspecified glaucoma
after Other and unspecified glaucoma

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Table

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Drugs most likely to be purchased after Other and unspecified glaucoma

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