Gestational diabetes (for exclusion)

GEST_DIABETES

cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule

Sex only females

180574

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Check conditions None

180574

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Filter registries

Hospital Discharge: ICD-10 O24.4
Hospital discharge: ICD-9 6488A
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 O24.4
Cause of death: ICD-9 6488A
Cause of death: ICD-8 $!$

9854

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

9854

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Check minimum number of events None

9854

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Include endpoints None

9854

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GEST_DIABETES

Extra metadata

First used in FinnGen datafreeze DF4
Parent code in ICD-10 O24
Name in latin Diabetes mellitus in gravidate apparens

Summary Statistics

Key figures

All Female Male
Number of individuals 9370 9370 -
Unadjusted prevalence (%) 3.04 5.40 -
Mean age at first event (years) 31.82 31.82 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.39 [0.97, 2.00] 7.5e-2 52
15 years 0.01 0.96 [0.58, 1.59] 8.7e-1 19
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: GEST_DIABETES – Gestational diabetes (for exclusion)
GWS hits: 7

Survival analyses between endpoints

Plot

before Gestational diabetes (for exclusion)
after Gestational diabetes (for exclusion)

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Drugs most likely to be purchased after Gestational diabetes (for exclusion)