Narcolepsy and cataplexy

G6_NARCOCATA

narcolepsy with cataplexy: Narcolepsy with cataplexy is a sleep disorder characterized by excessive day-time sleepiness associated with uncontrollable sleep urges and cataplexy (loss of muscle tone often triggered by pleasant emotions).

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G47.4

Hospital discharge: ICD-9 347[0-1]

Hospital discharge: ICD-8 34700

Cause of death: ICD-10 G47.4

Cause of death: ICD-9 347[0-1]

Cause of death: ICD-8 34700

KELA reimbursements: KELA codes 214

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

138

G6_NARCOCATA

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 G47

Name in latin Narcolepsia

Similar endpoints

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List of similar endpoints to Narcolepsy and cataplexy based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	135	72	63
Unadjusted prevalence (%)	0.04	0.04	0.05
Mean age at first event (years)	40.87	36.85	45.47

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_NARCOCATA – Narcolepsy and cataplexy
GWS hits: 0

Survival analyses between endpoints

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Plot

before Narcolepsy and cataplexy
after Narcolepsy and cataplexy

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Table

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Drugs most likely to be purchased after Narcolepsy and cataplexy

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