Panic disorder

F5_PANIC

panic disorder: An anxiety disorder characterized by multiple unexpected panic attacks with persistent concern of recurring attacks. Panic disorder may or may not be accompanied by agoraphobia.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 F41.0
Hospital discharge: ICD-9 3000B|3002B
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 F41.0
Cause of death: ICD-9 3000B|3002B
Cause of death: ICD-8 $!$

3779

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3779

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Check minimum number of events None

3779

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Include endpoints None

3779

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F5_PANIC

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F41
Name in latin Angor paroxysmalis episodicus

Summary Statistics

Key figures

All Female Male
Number of individuals 3614 2564 1050
Unadjusted prevalence (%) 1.17 1.48 0.78
Mean age at first event (years) 37.42 36.46 39.79

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.91 [2.51, 6.08] 1.4e-9 102
15 years 0.01 2.04 [1.21, 3.46] 7.6e-3 43
5 years 0.00 4.42 [2.43, 8.02] 1.0e-6 29
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_PANIC – Panic disorder
GWS hits: 1

Survival analyses between endpoints

Plot

before Panic disorder
after Panic disorder

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