Panic disorder

F5_PANIC

panic disorder: An anxiety disorder characterized by multiple unexpected panic attacks with persistent concern of recurring attacks. Panic disorder may or may not be accompanied by agoraphobia.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 F41.0
Hospital discharge: ICD-9 3000B|3002B
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 F41.0
Cause of death: ICD-9 3000B|3002B
Cause of death: ICD-8 $!$

3779

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3779

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Check minimum number of events None

3779

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Include endpoints None

3779

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F5_PANIC

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F41
Name in latin Angor paroxysmalis episodicus

Summary Statistics

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Key figures

All Female Male
Number of individuals 3614 2564 1050
Unadjusted prevalence (%) 1.17 1.48 0.78
Mean age at first event (years) 37.42 36.46 39.79

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.91 [2.51, 6.08] 1.4e-9 102
15 years 0.01 2.04 [1.21, 3.46] 7.6e-3 43
5 years 0.00 4.42 [2.43, 8.02] 1.0e-6 29
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_PANIC – Panic disorder
GWS hits: 1

Survival analyses between endpoints

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Plot

before Panic disorder
after Panic disorder

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