Generalized anxiety disorder

F5_GAD

generalized anxiety disorder: An anxiety disorder that is characterized by long-lasting anxiety that is not focused on any one object or situation.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 F41.1

Hospital discharge: ICD-9 3000C

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 F41.1

Cause of death: ICD-9 3000C

Cause of death: ICD-8 $!$

3330

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3330

Check minimum number of events None

3330

Include endpoints None

3330

F5_GAD

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 F41

Name in latin Perturbatio anxifera generalisata

Similar endpoints

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List of similar endpoints to Generalized anxiety disorder based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	3228	2253	975
Unadjusted prevalence (%)	1.05	1.30	0.72
Mean age at first event (years)	40.47	40.36	40.72

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.21 [1.82, 5.68]	6.1e-5	88
15 years	0.01	1.92 [1.14, 3.25]	1.4e-2	38
5 years	0.00	3.53 [2.05, 6.07]	5.1e-6	24
1 year	0.00	11.14 [5.83, 21.31]	3.1e-13	14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_GAD – Generalized anxiety disorder
GWS hits: 1

Survival analyses between endpoints

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Plot

before Generalized anxiety disorder
after Generalized anxiety disorder

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Table

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Drugs most likely to be purchased after Generalized anxiety disorder

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