Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

PheWeb

E4_HYTHY_AI_EXCL

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E8901|E8909|E23|D352|E0382|E05[1-9]|E0[0-2]

Hospital discharge: ICD-9 253

Hospital discharge: ICD-8 253

Cause of death: ICD-10 E8901|E8909|E23|D352|E0382|E05[1-9]|E0[0-2]

Cause of death: ICD-9 253

Cause of death: ICD-8 253

Operations: NOMESCO codes ^BAA60

8476

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

8459

Check minimum number of events None

8459

Include endpoints None

8459

E4_HYTHY_AI_EXCL

Extra metadata

First used in FinnGen datafreeze DF5

Similar endpoints

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List of similar endpoints to Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	8179	5878	2301
Unadjusted prevalence (%)	2.65	3.39	1.70
Mean age at first event (years)	52.50	52.09	53.54

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.02 [1.45, 2.82]	2.9e-5	447
15 years	0.01	1.12 [0.81, 1.54]	5.1e-1	200
5 years	0.00	2.24 [1.68, 2.98]	3.0e-8	138
1 year	0.00	5.75 [4.14, 8.00]	2.4e-25	67

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_HYTHY_AI_EXCL – Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT
GWS hits:

Survival analyses between endpoints

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Plot

before Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT
after Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

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