Other diabetes, wide definition


Takayasu arteritis: Takayasu arteritis (TAK) is a rare inflammatory large-vessel vasculitis primarily affecting the aorta and its major branches, but also other large vessels, causing stenosis, occlusion, or aneurysm.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions



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Filter registries

Hospital Discharge: ICD-10 E13
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E13
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints


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Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 47004 20078 26926
Unadjusted prevalence (%) 15.23 11.57 19.94
Mean age at first event (years) 56.44 56.13 56.68


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.30 [2.07, 2.57] 2.4e-51 6959
15 years 0.01 1.64 [1.50, 1.80] 1.4e-25 3749
5 years 0.00 2.39 [2.19, 2.60] 8.7e-88 1731
1 year 0.00 1.93 [1.65, 2.25] 2.3e-16 273

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: DM_OTHER_WIDE – Other diabetes, wide definition
GWS hits: 89

Survival analyses between endpoints


before Other diabetes, wide definition
after Other diabetes, wide definition

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Drugs most likely to be purchased after Other diabetes, wide definition