Other and unspecified disorders involving the immune mechanism, not elsewhere classified

DOID EFO MESH SNOMED PheWeb

D3_IMMUNEMECHANISMNAS

immune system disease: A disorder resulting from an abnormality in the immune system.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 D89.80+, D89.80+N08.2, D89.82, D89.82+N08.2, D89.89, D89.9

Hospital discharge: ICD-9 279[8-9]

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 D89.80+, D89.80+N08.2, D89.82, D89.82+N08.2, D89.89, D89.9

Cause of death: ICD-9 279[8-9]

Cause of death: ICD-8 $!$

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

588

D3_IMMUNEMECHANISMNAS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unspecified disorders involving the immune mechanism, not elsewhere classified based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

IgA nephropathy (IgA glomerulonefritis)

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	562	213	349
Unadjusted prevalence (%)	0.18	0.12	0.26
Mean age at first event (years)	47.80	43.89	50.19

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.13 [1.38, 7.10]	6.2e-3	44
15 years	0.01	1.58 [0.70, 3.60]	2.7e-1	16
5 years	0.00	3.66 [1.46, 9.19]	5.7e-3	18
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_IMMUNEMECHANISMNAS – Other and unspecified disorders involving the immune mechanism, not elsewhere classified
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other and unspecified disorders involving the immune mechanism, not elsewhere classified
after Other and unspecified disorders involving the immune mechanism, not elsewhere classified

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Table

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Drugs most likely to be purchased after Other and unspecified disorders involving the immune mechanism, not elsewhere classified

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