Other leukaemias of specified cell type

CD2_OTHER_LEUKAEMIA_SPECIFIED

leukemia: A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 C94

Hospital discharge: ICD-9 207[0-8]

Hospital discharge: ICD-8 207[0-2]

Cause of death: ICD-10 C94

Cause of death: ICD-9 207[0-8]

Cause of death: ICD-8 207[0-2]

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

CD2_OTHER_LEUKAEMIA_SPECIFIED

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Parent code in ICD-10 C81-C96

Name in latin Aliae leuc(h)aemiae typo cellulari specificato

Similar endpoints

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List of similar endpoints to Other leukaemias of specified cell type based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	49	25	24
Unadjusted prevalence (%)	0.02	0.01	0.02
Mean age at first event (years)	47.01	42.10	52.13

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_OTHER_LEUKAEMIA_SPECIFIED – Other leukaemias of specified cell type
GWS hits:

Survival analyses between endpoints

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Plot

before Other leukaemias of specified cell type
after Other leukaemias of specified cell type

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Table

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Drugs most likely to be purchased after Other leukaemias of specified cell type

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