Other and unspecified types of non-Hodgkin lymphoma

CD2_NONHODGKIN_NAS

non-Hodgkins lymphoma: Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage.

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 C85

Hospital discharge: ICD-9 200[8-9]

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 C85

Cause of death: ICD-9 200[8-9]

Cause of death: ICD-8 $!$

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

873

CD2_NONHODGKIN_NAS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Parent code in ICD-10 C81-C96

Name in latin Typi alii et non specificati lymphomatis non-Hodgkin

Similar endpoints

↥

List of similar endpoints to Other and unspecified types of non-Hodgkin lymphoma based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	847	355	492
Unadjusted prevalence (%)	0.27	0.20	0.36
Mean age at first event (years)	61.23	58.93	62.88

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.94 [3.40, 7.19]	6.6e-17	213
15 years	0.01	1.49 [1.03, 2.14]	3.2e-2	49
5 years	0.00	4.39 [3.04, 6.33]	2.3e-15	55
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: CD2_NONHODGKIN_NAS – Other and unspecified types of non-Hodgkin lymphoma
GWS hits: 1

Survival analyses between endpoints

↥

Plot

before Other and unspecified types of non-Hodgkin lymphoma
after Other and unspecified types of non-Hodgkin lymphoma

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Other and unspecified types of non-Hodgkin lymphoma

↥