Multiple myeloma and malignant plasma cell neoplasms

CD2_MULTIPLE_MYELOMA_PLASMA_CELL

multiple myeloma: A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 C90

Hospital discharge: ICD-9 203

Hospital discharge: ICD-8 203

Cause of death: ICD-10 C90

Cause of death: ICD-9 203

Cause of death: ICD-8 203

947

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

947

Check minimum number of events None

947

Include endpoints None

947

CD2_MULTIPLE_MYELOMA_PLASMA_CELL

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Parent code in ICD-10 C81-C96

Name in latin Myeloma multiplex et neoplasmata maligna plasmacytorum

Similar endpoints

↥

List of similar endpoints to Multiple myeloma and malignant plasma cell neoplasms based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	914	407	507
Unadjusted prevalence (%)	0.30	0.23	0.38
Mean age at first event (years)	65.94	64.69	66.94

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: CD2_MULTIPLE_MYELOMA_PLASMA_CELL – Multiple myeloma and malignant plasma cell neoplasms
GWS hits: 0

Survival analyses between endpoints

↥

Plot

before Multiple myeloma and malignant plasma cell neoplasms
after Multiple myeloma and malignant plasma cell neoplasms

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Multiple myeloma and malignant plasma cell neoplasms

↥