Leukaemia of unspecified cell type

CD2_LEUKAEMIA_NAS

leukemia: A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 C95
Hospital discharge: ICD-9 20[7-8]
Hospital discharge: ICD-8 207
Hospital discharge: excluded ICD-9 207[0-8]
Hospital discharge: excluded ICD-8 207[0-2]
Cause of death: ICD-10 C95
Cause of death: ICD-9 20[7-8]
Cause of death: ICD-8 207
Cause of death: excluded ICD-9 207[0-8]
Cause of death: excluded ICD-8 207[0-2]

202

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

182

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Check minimum number of events None

182

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Include endpoints None

182

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CD2_LEUKAEMIA_NAS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 C81-C96
Name in latin Leuc(h)aemiae typo cellulari non specificato

Summary Statistics

Key figures

All Female Male
Number of individuals 162 74 88
Unadjusted prevalence (%) 0.05 0.04 0.07
Mean age at first event (years) 54.56 50.81 57.71

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CD2_LEUKAEMIA_NAS – Leukaemia of unspecified cell type
GWS hits: 0

Survival analyses between endpoints

Plot

before Leukaemia of unspecified cell type
after Leukaemia of unspecified cell type

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Drugs most likely to be purchased after Leukaemia of unspecified cell type