In situ neoplasms

PheWeb

CD2_INSITU

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 D00-D09

Cause of death: ICD-10 D00-D09

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

Check minimum number of events None

Include endpoints

CD2_INSITU_ORAL

CD2_INSITU_DIGESTIVE

CD2_INSITU_EAR_RESP

CD2_INSITU_MELANOMA

CD2_INSITU_SKIN

CD2_INSITU_BREAST

CD2_INSITU_CERVIX_UTERI

CD2_INSITU_GENITAL

CD2_INSITU_OTHER_NOS

5760

CD2_INSITU

Extra metadata

Level in the ICD hierarchy 1

First used in FinnGen datafreeze DF6

Similar endpoints

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List of similar endpoints to In situ neoplasms based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	5583	3861	1722
Unadjusted prevalence (%)	1.81	2.23	1.28
Mean age at first event (years)	64.40	60.92	72.18

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.45 [1.88, 3.19]	3.6e-11	515
15 years	0.01	1.18 [0.92, 1.51]	1.9e-1	212
5 years	0.00	2.15 [1.71, 2.72]	9.9e-11	179
1 year	0.00	5.28 [4.04, 6.91]	5.0e-34	96

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_INSITU – In situ neoplasms
GWS hits: 3

Survival analyses between endpoints

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Plot

before In situ neoplasms
after In situ neoplasms

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Table

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Drugs most likely to be purchased after In situ neoplasms

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