Hodgkin lymphoma


non-Hodgkins lymphoma: Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 C81
Hospital discharge: ICD-9 201
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 C81
Cause of death: ICD-9 201
Cause of death: ICD-8 $!$


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 C81-C96
Name in latin Morbus Hodgkin

Summary Statistics

Key figures

All Female Male
Number of individuals 586 286 300
Unadjusted prevalence (%) 0.19 0.16 0.22
Mean age at first event (years) 47.12 41.82 52.17


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.61 [1.44, 4.71] 1.5e-3 82
15 years 0.01 1.29 [0.65, 2.58] 4.6e-1 32
5 years 0.00 2.67 [1.26, 5.67] 1.0e-2 21
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: CD2_HODGKIN_LYMPHOMA – Hodgkin lymphoma
GWS hits: 0

Survival analyses between endpoints


before Hodgkin lymphoma
after Hodgkin lymphoma

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Drugs most likely to be purchased after Hodgkin lymphoma