Benign neoplasm: Sigmoid colon

DOID EFO MESH SNOMED PheWeb

CD2_BENIGN_SIGMOID_COLON

sigmoid neoplasm: Tumors or cancer of the sigmoid colon.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 D12.5&

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 21136

Cause of death: ICD-10 D12.5&

Cause of death: ICD-9 $!$

Cause of death: ICD-8 21136

3609

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3609

Check minimum number of events None

3609

Include endpoints None

3609

CD2_BENIGN_SIGMOID_COLON

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D12

Name in latin Neoplasma benignum coli sigmoidei

Similar endpoints

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List of similar endpoints to Benign neoplasm: Sigmoid colon based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	3488	1676	1812
Unadjusted prevalence (%)	1.13	0.97	1.34
Mean age at first event (years)	63.78	62.37	65.08

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.44 [1.80, 3.33]	1.2e-8	392
15 years	0.01	1.24 [0.91, 1.70]	1.8e-1	176
5 years	0.00	2.72 [2.08, 3.57]	3.8e-13	145
1 year	0.00	3.88 [2.66, 5.64]	1.6e-12	41

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_BENIGN_SIGMOID_COLON – Benign neoplasm: Sigmoid colon
GWS hits: 2

Survival analyses between endpoints

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Plot

before Benign neoplasm: Sigmoid colon
after Benign neoplasm: Sigmoid colon

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Table

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Drugs most likely to be purchased after Benign neoplasm: Sigmoid colon

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