Leiomyoma of uterus


uterine fibroid: A benign smooth muscle neoplasm arising from the body of the uterus. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule

Sex only females


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 D25
Hospital discharge: ICD-9 218
Hospital discharge: ICD-8 21899
Cause of death: ICD-10 D25
Cause of death: ICD-9 218
Cause of death: ICD-8 21899


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D10-D36
Name in latin Leiomyoma uteri

Summary Statistics

Key figures

All Female Male
Number of individuals 25716 25716 -
Unadjusted prevalence (%) 8.33 14.82 -
Mean age at first event (years) 46.91 46.91 -


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.46 [0.40, 0.52] 6.5e-33 1141
15 years 0.00 0.35 [0.30, 0.40] 2.4e-52 478
5 years 0.00 0.34 [0.27, 0.43] 2.4e-20 91
1 year 0.00 0.53 [0.35, 0.80] 2.6e-3 24

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: CD2_BENIGN_LEIOMYOMA_UTERI – Leiomyoma of uterus
GWS hits: 49

Survival analyses between endpoints


before Leiomyoma of uterus
after Leiomyoma of uterus

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Drugs most likely to be purchased after Leiomyoma of uterus