Leiomyoma of uterus

CD2_BENIGN_LEIOMYOMA_UTERI

uterine fibroid: A benign smooth muscle neoplasm arising from the body of the uterus. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule

Sex only females

180574

Check conditions None

180574

Filter registries

Hospital Discharge: ICD-10 D25

Hospital discharge: ICD-9 218

Hospital discharge: ICD-8 21899

Cause of death: ICD-10 D25

Cause of death: ICD-9 218

Cause of death: ICD-8 21899

26622

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

26586

Check minimum number of events None

26586

Include endpoints None

26586

CD2_BENIGN_LEIOMYOMA_UTERI

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D10-D36

Name in latin Leiomyoma uteri

Similar endpoints

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List of similar endpoints to Leiomyoma of uterus based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	25716	25716	-
Unadjusted prevalence (%)	8.33	14.82	-
Mean age at first event (years)	46.91	46.91	-

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.46 [0.40, 0.52]	6.5e-33	1141
15 years	0.00	0.35 [0.30, 0.40]	2.4e-52	478
5 years	0.00	0.34 [0.27, 0.43]	2.4e-20	91
1 year	0.00	0.53 [0.35, 0.80]	2.6e-3	24

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_BENIGN_LEIOMYOMA_UTERI – Leiomyoma of uterus
GWS hits: 49

Survival analyses between endpoints

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Plot

before Leiomyoma of uterus
after Leiomyoma of uterus

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Table

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Drugs most likely to be purchased after Leiomyoma of uterus

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