Benign neoplasm of middle ear and respiratory system

CD2_BENIGN_EAR_RESP

cutaneous melanoma: A primary melanoma arising from atypical melanocytes in the skin. Precursor lesions include acquired and congenital melanocytic nevi, and dysplastic nevi. Several histologic variants have been recognized, including superficial spreading melanoma, acral lentiginous melanoma, nodular melanoma, and lentigo maligna melanoma.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 D14

Cause of death: ICD-10 D14

1481

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

1481

Check minimum number of events None

1481

Include endpoints

CD2_BENIGN_EAR_NASAL_SINUS

CD2_BENIGN_LARYNX

CD2_BENIGN_TRACHEA

CD2_BENIGN_BRONCHUS_LUNG

CD2_BENIGN_RESPIRATORY_NOS

1758

CD2_BENIGN_EAR_RESP

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D10-D36

Name in latin Neoplasma benignum auris mediae sive systematis respiratorii

Similar endpoints

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List of similar endpoints to Benign neoplasm of middle ear and respiratory system based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1696	719	977
Unadjusted prevalence (%)	0.55	0.41	0.72
Mean age at first event (years)	53.91	50.94	56.10

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	1.16 [0.62, 2.16]	6.4e-1	218
15 years	0.00	0.78 [0.45, 1.34]	3.6e-1	104
5 years	0.00	1.72 [1.09, 2.73]	2.1e-2	60
1 year	0.00	3.68 [2.14, 6.35]	2.6e-6	24

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_BENIGN_EAR_RESP – Benign neoplasm of middle ear and respiratory system
GWS hits: 0

Survival analyses between endpoints

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Plot

before Benign neoplasm of middle ear and respiratory system
after Benign neoplasm of middle ear and respiratory system

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Table

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Drugs most likely to be purchased after Benign neoplasm of middle ear and respiratory system

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