Benign neoplasm: Descending colon

CD2_BENIGN_DESCENDING_COLON

colonic neoplasm: A benign or malignant neoplasm that affects the colon. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. Colonic adenomas always exhibit epithelial dysplasia and are considered premalignant neoplasms.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 D12.4&

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 21135

Cause of death: ICD-10 D12.4&

Cause of death: ICD-9 $!$

Cause of death: ICD-8 21135

1163

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1163

Check minimum number of events None

1163

Include endpoints None

1163

CD2_BENIGN_DESCENDING_COLON

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D12

Name in latin Neoplasma benignum coli descendentis

Similar endpoints

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List of similar endpoints to Benign neoplasm: Descending colon based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1123	496	627
Unadjusted prevalence (%)	0.36	0.29	0.46
Mean age at first event (years)	65.27	63.05	67.02

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.73 [1.57, 4.74]	3.6e-4	122
15 years	0.01	1.39 [0.78, 2.49]	2.7e-1	60
5 years	0.00	2.85 [1.76, 4.61]	2.1e-5	49
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_BENIGN_DESCENDING_COLON – Benign neoplasm: Descending colon
GWS hits: 0

Survival analyses between endpoints

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Plot

before Benign neoplasm: Descending colon
after Benign neoplasm: Descending colon

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Table

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Drugs most likely to be purchased after Benign neoplasm: Descending colon

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