Benign neoplasm: Anus and anal canal

CD2_BENIGN_ANUS_ANAL_CANAL

anal neoplasm: A benign or malignant neoplasm that affects the anal canal or anal margin. Representative examples of benign neoplasms include squamous papilloma and papillary hidradenoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and melanoma.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 D12.9&

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 D12.9&

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

588

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

588

Check minimum number of events None

588

Include endpoints None

588

CD2_BENIGN_ANUS_ANAL_CANAL

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D12

Name in latin Neoplasma benignum ani

Similar endpoints

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List of similar endpoints to Benign neoplasm: Anus and anal canal based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	567	287	280
Unadjusted prevalence (%)	0.18	0.17	0.21
Mean age at first event (years)	62.16	59.77	64.62

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.25 [1.46, 3.47]	2.6e-4	80
15 years	0.01	1.06 [0.64, 1.75]	8.2e-1	36
5 years	0.00	1.75 [0.96, 3.16]	6.6e-2	26
1 year	0.00	3.33 [1.51, 7.36]	2.9e-3	10

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_BENIGN_ANUS_ANAL_CANAL – Benign neoplasm: Anus and anal canal
GWS hits: 0

Survival analyses between endpoints

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Plot

before Benign neoplasm: Anus and anal canal
after Benign neoplasm: Anus and anal canal

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Table

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Drugs most likely to be purchased after Benign neoplasm: Anus and anal canal

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