Benign neoplasm: Adrenal gland

CD2_BENIGN_ADRENAL

extra-adrenal sympathetic paraganglioma: A benign or malignant sympathetic paraganglioma arising from paraganglia outside the adrenal gland. Clinical symptoms are related to secretion of catecholamines. Representative examples include the superior and inferior paraaortic and bladder paragangliomas.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 D35.0&
Hospital discharge: ICD-9 2270
Hospital discharge: ICD-8 2260
Cause of death: ICD-10 D35.0&
Cause of death: ICD-9 2270
Cause of death: ICD-8 2260

1584

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1269

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Check minimum number of events None

1269

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Include endpoints None

1269

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CD2_BENIGN_ADRENAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D35
Name in latin Neoplasma benignum glandulae suprarenalis

Summary Statistics

Key figures

All Female Male
Number of individuals 1235 733 502
Unadjusted prevalence (%) 0.40 0.42 0.37
Mean age at first event (years) 61.65 59.92 64.18

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 4.19 [2.23, 7.85] 8.1e-6 73
15 years 0.01 2.33 [1.27, 4.26] 6.2e-3 36
5 years 0.00 3.36 [1.71, 6.57] 4.1e-4 28
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CD2_BENIGN_ADRENAL – Benign neoplasm: Adrenal gland
GWS hits: 2

Survival analyses between endpoints

Plot

before Benign neoplasm: Adrenal gland
after Benign neoplasm: Adrenal gland

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Drugs most likely to be purchased after Benign neoplasm: Adrenal gland