Benign neoplasm: Adrenal gland

CD2_BENIGN_ADRENAL

extra-adrenal sympathetic paraganglioma: A benign or malignant sympathetic paraganglioma arising from paraganglia outside the adrenal gland. Clinical symptoms are related to secretion of catecholamines. Representative examples include the superior and inferior paraaortic and bladder paragangliomas.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 D35.0&

Hospital discharge: ICD-9 2270

Hospital discharge: ICD-8 2260

Cause of death: ICD-10 D35.0&

Cause of death: ICD-9 2270

Cause of death: ICD-8 2260

1584

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1269

Check minimum number of events None

1269

Include endpoints None

1269

CD2_BENIGN_ADRENAL

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D35

Name in latin Neoplasma benignum glandulae suprarenalis

Similar endpoints

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List of similar endpoints to Benign neoplasm: Adrenal gland based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1235	733	502
Unadjusted prevalence (%)	0.40	0.42	0.37
Mean age at first event (years)	61.65	59.92	64.18

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	4.19 [2.23, 7.85]	8.1e-6	73
15 years	0.01	2.33 [1.27, 4.26]	6.2e-3	36
5 years	0.00	3.36 [1.71, 6.57]	4.1e-4	28
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_BENIGN_ADRENAL – Benign neoplasm: Adrenal gland
GWS hits: 2

Survival analyses between endpoints

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Plot

before Benign neoplasm: Adrenal gland
after Benign neoplasm: Adrenal gland

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Table

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Drugs most likely to be purchased after Benign neoplasm: Adrenal gland

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