Malignant neoplasm of peripheral nerves and autonomic nervous system

C3_PERIPHERAL_NERVES_AUTONOMIC3_NERVESYSTEM

tumour of cranial and spinal nerves: ['A benign or malignant neoplasm arising from a peripheral nerve or the perineural sheaths.', 'Neoplasms which arise from peripheral nerve tissue. This includes NEUROFIBROMAS; SCHWANNOMAS; GRANULAR CELL TUMORS; and malignant peripheral NERVE SHEATH NEOPLASMS. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp1750-1)']

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Cause of death: ICD-10 C47

Cause of death: ICD-9 1928

Cause of death: ICD-8 192[4-5]

Cancer registry: Topography ICD-O-3 C47

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

C3_PERIPHERAL_NERVES_AUTONOMIC3_NERVESYSTEM

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Malignant neoplasm of peripheral nerves and autonomic nervous system based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

Unadjusted prevalence (%)

0.01

Mean age at first event (years)

37.63

32.08

41.59

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Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_PERIPHERAL_NERVES_AUTONOMIC3_NERVESYSTEM – Malignant neoplasm of peripheral nerves and autonomic nervous system
GWS hits:

Survival analyses between endpoints

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Plot

before Malignant neoplasm of peripheral nerves and autonomic nervous system
after Malignant neoplasm of peripheral nerves and autonomic nervous system

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Table

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Drugs most likely to be purchased after Malignant neoplasm of peripheral nerves and autonomic nervous system

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