Malignant neoplasm of peripheral nerves and autonomic nervous system

C3_PERIPHERAL_NERVES_AUTONOMIC3_NERVESYSTEM

tumour of cranial and spinal nerves: ['A benign or malignant neoplasm arising from a peripheral nerve or the perineural sheaths.', 'Neoplasms which arise from peripheral nerve tissue. This includes NEUROFIBROMAS; SCHWANNOMAS; GRANULAR CELL TUMORS; and malignant peripheral NERVE SHEATH NEOPLASMS. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp1750-1)']

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Cause of death: ICD-10 C47

Cause of death: ICD-9 1928

Cause of death: ICD-8 192[4-5]

Cancer registry: Topography ICD-O-3 C47

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

C3_PERIPHERAL_NERVES_AUTONOMIC3_NERVESYSTEM

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Malignant neoplasm of peripheral nerves and autonomic nervous system based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	24	10	14
Unadjusted prevalence (%)	0.01	0.01	0.01
Mean age at first event (years)	37.63	32.08	41.59

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_PERIPHERAL_NERVES_AUTONOMIC3_NERVESYSTEM – Malignant neoplasm of peripheral nerves and autonomic nervous system
GWS hits:

Survival analyses between endpoints

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Plot

before Malignant neoplasm of peripheral nerves and autonomic nervous system
after Malignant neoplasm of peripheral nerves and autonomic nervous system

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Drugs most likely to be purchased after Malignant neoplasm of peripheral nerves and autonomic nervous system

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